Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of YWHAq in serum, plasma, tissue homogenates, cell lysates, cell culture supernates. Due to the 99.6% homology of the sequence among different species, the kit can be used to detect human, mouse and rat samples.
Target Information: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]